Abstract

LANDINEZ PARRA, Nancy Stella; GARZON ALVARADO, Diego Alexander  and  CARDOZO DE MARTINEZ, Carmen Alicia. Approach to chondrocytes culture in National University of Colombia.: A technical report. Rev Cubana Invest Bioméd [online]. 2010, vol.29, n.1, pp. 0-0. ISSN 1561-3011.

The loss of a tissue or its function due to congenital defects, disease or trauma, is one of the major, frequent and expensive problems challenging the human medicine. The articular cartilage degeneration is known as osteoarthritis (OA), which is characterized by enzyme and mechanical damage of extracellular matrix, generating pain and lead to the loss of movement and articular instability. The articular cartilage has low repair ability due to its avascularization. The aim of present paper is to make an approach to cartilage tissue engineering to establish the theoretical basis on this subject to understand the tissue in vitro behavior allowing in the future, to construct a cartilage equivalent by means of current procedures of tissue engineering, offering a response to social problems and of the public health. Conclusions from present paper make easy futures researches in the field of articular cartilage regeneration and its clinical application and also, providing the bases to planning in vivo and in vitro researches to deepen in this subject.

Keywords : Articular cartilage; tissue engineering; chondrocytes; growth factors; bioreactors.

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