Abstract

LEMUS VALDES, María Teresa  and  CASTILLO HERRERA, José Arcides. Studies about the genetic bases of high blood pressure. Rev Cubana Invest Bioméd [online]. 2013, vol.32, n.1, pp. 8-20. ISSN 0864-0300.

It is known that among the main causes of the increase in high blood pressure levels, the causes of both genetic origin and environmental origin play an important role, thus classifying it as a multifactor disease. The genetic bases are well established in the disease and the development in the field of molecular genetics has been vertiginous. That is the reason why the advances in the knowledge of the genetic alterations that cause high blood pressure are of paramount importance. A review about the different studies that were carried out recently in relation to the genetic basis of high blood pressure was made. The information shown for the future in these analyses is of great importance for high-risk patients' selection, the implementation of adequate preventive measures and the development of both new drugs and individualized therapy.

Keywords : Family aggregation; candidate genes; segregation; allelic associations; ligament.

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