Abstract

HERNANDEZ REQUEJO, Daymé; ABAD LAMOTH, Yoandra  and  VALLE CARVAJAL, Elizabeth B. CD4+ T-lymphocytes and viral load in elderly patients with HIV/AIDS who receive antiretroviral treatment. Rev Cubana Invest Bioméd [online]. 2013, vol.32, n.2, pp. 139-146. ISSN 0864-0300.

Background: Infection with the Human Immunodeficiency Virus (HIV) is a major health problem. The functional capacity of the immune system gradually declines with aging. Objective: To demonstrate that the elderly patients with HIV/AIDS who follow treatment with antiretroviral drugs present a fall in viral load and a rise in the CD4+ T-lymphocytes with this treatment. Methods: A cross-sectional prospective observational study was conducted in 44 HIV/AIDS patients attended in the Medical Services offered by IPK who received treatment with different antiretroviral schemes. Results: It was observed that there was an average rise of 97 cel/µL in the CD4+ T-lymphocytes, as well as an average fall of 3 583 cp/µL in viral load after the antiretroviral treatment. Conclusions: With this study, we can conclude that there was a rise in CD4+ T-lymphocytes and a fall in the viral load in the elderly patients with HIV/AIDS who followed treatment with antiretroviral drugs, what evidences the immunological reconstitution and virologic control of these patients with the use of antiretroviral therapy.

Keywords : immunodeficiency virus (HIV); CD4+ T-lymphocytes; elderly.

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