Abstract

GOYA BATISTA, Yordana et al. Comparison of two serological methods for the diagnosis IgG antibody against in newborn. Rev Cubana Invest Bioméd [online]. 2014, vol.33, n.4, pp. 405-413. ISSN 1561-3011.

Dissimilar are the methods used to determine the seroprevalence of IgG antibodies against to Toxoplasma gondii in different samples. In this research were compared to Indirect Immunofluorescence and Toxoplasma Latex by Brunelli to prove which of them is the most sensitive and specific to determine seroprevalence of IgG anti-Toxoplasma gondii in newborn in Neonatology Service at Lenin Hospital of Holguin Province, Cuba is the main objective. Thirty samples were analyzed of newborns treated in Neonatology Service using these methods, besides two working groups were formed. The sensitivity and specificity of Indirect Immunofluorescence were 100 % and 95 % respectively and Toxoplasma latex reported a sensitivity of 96.1 % and a specificity of 89.6 %. These results showed that the Indirect Immunofluorescence Technique is the most useful for these diagnostic and this result are similar with others investigations.

Keywords : Indirect Immunofluorescence; Toxoplasma latex; IgG Antibody; Toxoplasmosis; Sensitivity; Specificity; Newborn.

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