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Revista Cubana de Investigaciones Biomédicas
On-line version ISSN 1561-3011
Abstract
SANCHEZ ARTIGAS, Rolando et al. Toxoplasmosis: an unsolved problem. Rev Cubana Invest Bioméd [online]. 2016, vol.35, n.3, pp. 272-283. ISSN 1561-3011.
One third of the world population have antibodies against Toxoplasma gondii. Human beings may be infected by sporozoites from cat faeces contaminating the ground, fruits, vegetables and water, by bradyzoites present in insufficiently cooked or improperly manipulated meat, or by trophozoites circulating during the hematogenous phase. Fetuses may be infected through the placenta, and seronegative individuals by solid organs transplanted or transfused with formed elements of the blood. These are the risk groups most prone to develop serious, life-threatening forms of the disease. Recent studies confirm the relationship of this infection to neuropsychiatric disorders, particularly schizophrenia, as well as its relationship to traffic accidents among seropositive drivers. It is paramount to bear in mind the ways in which the disease may be acquired and the corresponding prevention measures, especially for persons who have never had the disease.
Keywords : Toxoplasma gondii; sporozoites; bradyzoites; trophozoites; neuropsychiatric; Th2 cells.