SciELO - Scientific Electronic Library Online

 
vol.39 issue3Reasons for blood donor deferral in a Southern Peruvian hospitalHistomorphometric study of human thyroid follicles by digital holographic microscopy author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Cubana de Investigaciones Biomédicas

On-line version ISSN 1561-3011

Abstract

TOLEDO HIDALGO, Deimarys; DIAZ ROJAS, Pedro A.; TORRES BATISTA, Marylú  and  SANCHEZ ANTA, Alejandro. Nuclear optical density as a diagnostic indicator in papillary thyroid carcinoma. Rev Cubana Invest Bioméd [online]. 2020, vol.39, n.3  Epub Sep 01, 2020. ISSN 1561-3011.

Background:

Papillary thyroid carcinoma is the most frequent cause of endocrine cancer. It is an histological variant with the best prognosis, however, sometimes it is a reason for significant diagnostic doubts with other variants of torpid evolution, which makes it difficult for a greater number of patients to benefit from an individualized and conservative treatment.

For this reason, studies are developed in which more and more morphometric and densitometric procedures are added, which allow reducing the subjectivity in the histopathological diagnosis and could represent a tool of great value.

Objective:

To determine the nuclear optical density in papillary thyroid carcinoma.

Method:

A morphometric study of a series of cases was carried out with 12 patients with this histopathological diagnosis, attended at the Vladimir Ilich Lenin University Provincial Hospital. We chose 36 fields and 965 cell nuclei were measured, which constituted the study sample.

Nuclear optical density was determined as a morphometric indicator of papillary thyroid carcinoma.

Results:

The value of nuclear optical density was 1, 14. It is considered low.

Conclusion:

Nuclear optical density of papillary thyroid carcinoma was determined in the studied cases that may contribute to histopathological diagnosis.

Keywords : thyroid; papillary thyroid carcinoma; morphometry; optical densitometry; chromatin texture.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )