Resumo

GOMEZ-CONDE, Santa Yarelis et al. SAPHO syndrome in an adolescent with localized scleroderma: case report. Rev Cuba Reumatol [online]. 2023, vol.25, n.1  Epub 30-Jan-2024. ISSN 1817-5996.

SAPHO syndrome is a chronic autoinflammatory disease that encompasses a series of cutaneous and osteoarticular manifestations that include synovitis, acne, pustulosis, hyperostosis, and osteitis. We present the case of an 18-year-old male patient, with a history of localized scleroderma diagnosed by biopsy 3 years ago, who debuted with skin and osteoarticular lesions 6 months after discontinuing treatment with methotrexate and colchicine, for said history. An MRI suggestive of sacroiliitis with the presence of bone edema was reported, and bone scintigraphy revealed uptake areas with a bull's head image in the sternoclavicular joint, suggesting SAPHO syndrome. It was decided to reincorporate methotrexate and colchicine, evolving satisfactorily. No similar reports were found coexisting with these two entities that have treatment with the same drugs as a point in common.

Palavras-chave : colchicine; localized scleroderma; methotrexate; SAPHO syndrome.

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