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Revista Cubana de Estomatología

Print version ISSN 0034-7507

Abstract

FLORES ALVARADO, Sergio Alberto; MORALES CASAS, José; SEPULVEDA INFANTE, Rogelio  and  ROMERO DE LEON, Elías. Odontogenic carcinoma of clear cells. Rev Cubana Estomatol [online]. 2011, vol.48, n.1, pp. 69-76. ISSN 0034-7507.

Clear cell odontogenic carcinoma is a rare malignant odontogenic neoplasm, with a predilection for the anterior segment of the jaws, and presenting basically in women between the fifth and seventh decades of life. CCOC is composed histopathologycally by strands or groups of cells showing clear cytoplasm associated with cells showing eosinophilic cytoplasm and some times with tall columnar cells that resambled ameloblasts. CCOC is considered a low-grade malignancy but in some cases its behavior is aggressive giving local and distant metastasis, so the recommended treatment is a radical resection and follows the patient very close. CCOC should be diferenciated microscopically from other local and metastatic lesions that are composed with clear cells also, in order to render a proper diagnosis and treatment. We are presenting a clinical case corresponding to a 69 years old female patient, with a 10 year history of a slow growing anterior mandibular lesion without lymph node or distant metastasis, with a biopsy diagnosis of clear cell odontogenic carcinoma, the patient was treated by partial resection of the anterior mandible and reconstructed with a titanium plate.

Keywords : clear cell odontogenic carcinoma; clear cell ameloblastoma; clear cell tumors; odontogenic tumors.

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