Abstract

CLAPE LAFFITA, Oneyda; HODELIN TABLADA, Ricardo; BERMUDEZ CAMPS, Isis  and  TORRES LA ROSA, José Ángel. Reacciones adversas e interacciones medicamentosas en pacientes con edema cerebral. Rev Cubana Farm [online]. 1999, vol.33, n.2, pp. 116-120. ISSN 1561-2988.

A study was carried out in the Intensive and Intermediate Care Units of "Saturnino Lora" Teaching Clinicosurgical Hospital with the purporse of assessing adverse drug reactions and drug interactions detected in treating brain edema. The method of intensive surveillance of the hospitalized patients was used in a sample of 65 cases accoirding to set experimental conditions. Date obtained was evaluated by Narnajo’s and Karch-Lasagna’s algoritthms and also, benefit-risk of each treatment and adequate statistical processing were also analysed. 114 adverse drug reactions and 40 drug interactions were detected, wihch were first related to clinical and demographic aspects and then pharmacologically analyzed. Therapeutic measures for the staff were proposed as well as recommendations for patients were made so as to reduce the risks that treatments may cause.

Keywords : BRAIN EDEMA [complications]; INTENSIVE CARE; INTERMEDIATE CARE FACILITIES; MANNITOL [adverse effects]; FUROSEMIDE [adverse effects].

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