Abstract

PAYO HILL, Armando; SANDOVAL LOPEZ, Daisy; VELEZ CASTRO, Hermán  and  OQUENDO SUAREZ, Marledis. Alcaloides en la especie cubana Croton micradenus Urb. Rev Cubana Farm [online]. 2001, vol.35, n.1, pp. 61-65. ISSN 1561-2988.

The study of the content of alkaloids in the leaves and stems of the Croton micradenus Urb Cuban endemic species, which is potentially medicinal, was conducted. Organic solvents and chromatographic methods of separation by column and plate were used for the extraction and purification of these metabolites. 4 of the 6 isolated alkaloids, 3 of them morphinandienones: ocobotrine, sinoacutine and 8,14-dihydrosalutaridine and an aporphine (Isobol-dine) were characterized by spectroscopic methods of UV, IR, Mass and NMR ¹H and ¹³C, as well as by the measurement of their physical constants.

Keywords : ALKALOIDS [chemistry]; PLANTS, MEDICINAL; PLANT EXTRACTS [chemistry]; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, THIN LAYER; ALKALOIDS [isolation & purification]; SPECTRUM ANALYSIS, MASS [methods].

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