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Revista Cubana de Farmacia

On-line version ISSN 1561-2988

Abstract

FERNANDEZ SERRET, Alfredo; AGUILERA CABRERA, Yeni; MORALES LACARRERE, Iván  and  ALONSO JIMENEZ, Esther. Validación de los métodos analíticos para la identificación y cuantificación del dextrometorfano jarabe. Rev Cubana Farm [online]. 2002, vol.36, n.1, pp. 28-34. ISSN 1561-2988.

The technique described in the USP 23 was applied to carry out the quality control of the dextrometorphan syrup . The reliability of this method was proved by evaluating the accuracy, exactitude, lineality and specificity. The determination of the organoleptic characteristics, pH and content per bottle were also included as own trials of liquid drugs for oral adminstration or for external use.

Keywords : DEXTROMETORPHAN [pharmacology]; QUALITY CONTROL; HIGH PRESSURE LIQUID CHROMATOGRAPHY; COUGH; DRUGS QUALITY [drug therapy]; CHEMISTRY, PHARMACEUTICAL.

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