Abstract

DIAZ POLANCO, Iverlis; GARCIGA HERNANDEZ, María Rosa; PEREZ CRESPO, Ana Ibis  and  ROBERTO CORDOVES, Yamilka. Caracterización de un sistema acuoso de recubrimiento de película para tabletas. Rev Cubana Farm [online]. 2002, vol.36, n.3, pp. 147-151. ISSN 1561-2988.

The characterization of suspensions for coating placebo nuclei was developed in aqueous systems with white polycoat 2 as a base. The suspensions were colored with 3 different Lake coloring matters. The density of these suspensions was evaluated with diverse percentages of disperse solids (10-20 %). An increase of them was observed with the increment of disperse solids. The coating of placebo nuclei of different die sizes was carried out and the coated tablets were submitted to a study on the stability of color to light by evaluating their optical density. The following order was established: yellow > blue > red. A study on the humidity gain of the coated tablets was conducted at various relative humidities in stabilized hydrostats and the efficiency of the coating system for protecting tablets under normal conditions of relative humidity was confirmed. The physical and chemical parameters evaluated in placebo nuclei and coated tablets fulfilled the established limits and some of them were discussed.

Keywords : SUSPENSIONS [analysis]; TABLETS, ENTERIC COATED [analysis]; PHARMACEUTIC AIDS.

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