Abstract

FERNANDEZ MONAGAS, Sol Amalia; GRA RIOS, Gisela; BARRIOS ALVAREZ, María Aurora  and  CASTINEIRA DIAZ, Mirta. Estabilidad del inyectable de fosfato de disopiramida (13 mg/mL). Rev Cubana Farm [online]. 2003, vol.37, n.2, pp. 0-0. ISSN 1561-2988.

Among the drugs presently used to treat cardiovascular disorders, we may find disopyramide phosphate, a type I anti-arrhythmia agent which stabilizes the membrane potential at rest. One of the dosage forms is the injection, at a dose of 13 mg/mL for the basis, therefore, this paper makes an accelerated study of the stability and the analysis of the lifetime of 3 batches of this injectable form. Under the test conditions, the drug turned out to be stable and its expiry date was set at 2 years.

Keywords : DISOPYMIDE; DRUGSTABILITY; ANTI-ARRYTMMIA AGENTS..