Abstract

RODRIGUEZ CHANFRAU, Jorge E et al. Effectiveness of washout process to obtain calcium and magnesium citrate at bench scale. Rev Cubana Farm [online]. 2010, vol.44, n.1, pp.5-12. ISSN 0034-7515.

As part of the technological process optomization to obtain calcium citrate and magnesium from dolomites, we studied at bench scale, the washout stage to decrease the free citric acid content. Washout variants allowed to decrease the free citric acid content under 3 %, whereas the calcium and magnesium values are similar to those of batch before to carry out the wahout process. On the other hand, toxicity study in rats, proved that the batches where different washout variables were applied not provoke gastric irritability at doses of 2 000 mg/kg of body weight confirming that above mentioned established process is approproate to guarantee the raw material quality.

Keywords : Calcium citrate and magnesium; washout; dolomite; citric acid.

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