SciELO - Scientific Electronic Library Online

 
vol.44 issue4Study of chemical compatibility of Rhizophora mangle L. dry extract and of different pharmaceutical excipients using thermal analysisPharmacokinetics and pharmacodynamics author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Cubana de Farmacia

Print version ISSN 0034-7515On-line version ISSN 1561-2988

Abstract

ARBOLEDA ECHAVARRIA, Carolina  and  MEJIA GALLON, Amanda Inés. Induction of lacasa activity in Ganoderma sp and the antioxidant activity of its biomass. Rev Cubana Farm [online]. 2010, vol.44, n.4, pp.519-532. ISSN 0034-7515.

The Basidiomycetes have a great potential for the production of wide application enzymes in the pharmaceutical, alimentary, food industry and the water and soils recovery. In Colombia come types of Basidiomycetes fungi including the Ganoderma.sp that is additionally worldwide recognized by its medicinal effects. In present paper authors assessed the influence of invironment pH and of the inducers: copper and Angustifolia, kunth sawdust in the production of lacase enzyme and also in the antioxidant activity of DPPH and ABTS.+ radicals. The variables analyzed at three levels by Design Expert 6 software demonstrated that the better combination of variables for a maximal enzyme expression was obtained using the 0.75 % Angustifolia kunth sawdust, 250 mM of copper and pH 5; the great percentage of the ABTS radical inhibition (86 %) was observed at a pH 4 without copper addition and with a percentage of sawdust of 1.50 and the greater percentae of DPPH radical inhibition (57 %) was observed at a pH 6 without sawdust and copper addition.

Keywords : Ganoderma; lacase; antioxidant activity.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License