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Revista Cubana de Farmacia
Print version ISSN 0034-7515
Abstract
RODRIGUEZ CHANFRAU, Jorge Enrique and LOPEZ HERNANDEZ, Orestes Darío. Filtration time for calcium cytrate and magnesium from the Cuban dolomite. Rev Cubana Farm [online]. 2011, vol.45, n.3, pp. 449-453. ISSN 0034-7515.
Calcium and magnesium citrate is a raw material of pharmaceutical quality obtained from Cuban dolomites to be used in those people with deficiency in these two minerals. As part of the technological process optimization, the filtering time was studied to evaluate the possible behaviour at higher scales. To this end, one scale-down study was made to determine the conditions at bench scale by keeping the same power consumption per volume unit. The fundamental filtering equation allowed determining the time for this operation. The results of this study showed that the resistance value of the filtering material was Rm= 6.08 · 1010 m-1 and the resistance of the mass was a= 1.239 · 1010 m·kg-1 at constant pressure (Dp= 9.99 × 104 kg/m·s2). The filtration time was 494.6 s (8,24 ± 3,0 min). The results showed that the filtration time was correct for the studied technological process and the scale up study demonstrated the feasibility of the filtration process.
Keywords : calcium and magnesium citrate; filtration; filtration time; dolomite.