Revista Cubana de Farmacia
version ISSN 0034-7515
ALVAREZ CASTELLO, Mirta et al. Aspirin desensitization in a patient who exhibit intolerance to non-steroidal anti-inflammatories. Rev Cubana Farm [online]. 2011, vol.45, n.4, pp. 597-603. ISSN 0034-7515.
Aspirine is one of the most widely used drugs worldwide. The patients suffering from heart diseases require long-term treatment with this drug, which is banned to those having adverse reactions. The international literature collects information on the use of desensitization therapies in patients who do not exhibit tolerance to this medicine, following different protocols with satisfactory results. This paper described the first aspirin desensitization procedure, which was performed at «Calixto García» university hospital, and the performance protocol. There was not any other case of this type reported in the national literature. The patient can presently take 125 mg of aspirin daily without suffering adverse events. It was considered that the desensitization process is an effective therapeutic action for patients who are aspirin sensitive and who have specific diseases that warrant this procedure.
Keywords : drug hypersensitivity; aspirin; non-steroidal anti-inflammatory agents; aspirin desensitization.