SciELO - Scientific Electronic Library Online

vol.48 issue1Formulation of hard capsules from Tamarindus indica L.In vitro effects of policosanol (Saccharum officinarum L wax alcohols) on the 5-lipooxygenase enzyme author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista Cubana de Farmacia

Print version ISSN 0034-7515


NAPOLES LOPEZ, Raúl; RODRIGUEZ AMADO, Jesús Rafael; RODRIGUEZ ANTOMACHI, Maricel  and  LAFOURCADE PRADA, Ariadna. Validation of flavonoid quantification method in Passiflora incarnata L. tablets. Rev Cubana Farm [online]. 2014, vol.48, n.1, pp.129-138. ISSN 0034-7515.

Introduction: to validate the flavonoid quantification method on Passiflora incarnata L. tablets by using quercetine as standard. Methods: selectivity, linearity, accuracy, precision and robustness were evaluated, using USP 30 and the regulations of the Center for the State Control of Drug Quality (CECMED). Results: under the conditions of this study, the method is selective, linear in a range of 60 to 140 % of flavonoid concentration. It showed accuracy and precision with global relative standard deviation of 0.67 %. The results did not significantly vary when the analytical conditions changed. Conclusions: under the established conditions, this method is reliable and allows obtaining appropriate results for the intended use.

Keywords : validation; flavonoids; Passiflora incarnata L..

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )