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Revista Cubana de Farmacia

Print version ISSN 0034-7515On-line version ISSN 1561-2988


CALIL BRONDANI, Juliana  and  PALERMO MANFRON, Melânia. Chemical constituents, biological activity and therapeutic uses, of Scutia buxifolia Reissek.. Rev Cubana Farm [online]. 2015, vol.49, n.3. ISSN 0034-7515.

Scutia buxifolia has been used in the treatment of a number of diseases, which includes bacterial and fungal infections, hypertension, Alzheimer's Disease and cancer. S. buxifolia contains biologically active compounds such as flavonoids, steroids, tanins, lipids, terpens and alkaloids. A range of biological activities has been found from plant extract and fractions, including antioxidant, acetylcholinesterase inhibitor, antiviral and antibiotic. Some studies about the potential toxicity were performed; however the results are not conclusive, suggesting that a single administration of the extract is safe, whereas prolonged use has deleterious effects for the body. The revised databases were SciELO, PubMed, ScienceDirect and Portal da Capes considering studies between 1964 and 2014 and by searching for terms like Scutia buxifolia, Rhamnaceae family, Scutia buxifolia Constituents, Scutia buxifolia use and OECD.

Keywords : biological activities; Scutia buxifolia; chemical constituents; toxicity.

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