Abstract

PESTANA KNIGHT, Elia Margarita; SARDINAS HERNANDEZ, Norberto; TRUJILLO MATIENZO, Clemente  and  DE ARMAS ALVAREZ, Ana Isabel. Influencia de la medicación antiepiléptica sobre los resultados escolares de niños epilépticos. Rev Cubana Pediatr [online]. 1996, vol.68, n.1, pp. 26-31. ISSN 1561-3119.

With the aim of knowing the influence of antiepileptic drug therapy on learning outcomes, 30 children with partial epileptic crisis that go to normal primary schools, were studied. These data were collected in family interviews: antiepileptic drug therapy used, dose in blood, and academic outcomes in the last school course correlated with the variables studied with the multiple correlation test. Twenty four children (80 %) received monotherapy treatment, and six (20 %) received politherapy. Phenytoin significantly correlated (p < 0.005) with M school outcomes. There is a relation of the increased drug levels in blood with the worst academic results.

Keywords : EPILEPSY [drug therapy]; INTELLIGENCE [drug effects]; CARBAMAZEPINE [adverse effects]; CARBAMAZEPINE [blood]; PHENYTOIN [adverse effects]; PHENYTOIN [blood]; PRIMIDONE [adverse effects]; PRIMIDONE [blood]; PHENOBARBITAL [adverse effects]; PHENOBARBITAL [blood]; LEARNING.