Abstract

CHRISTIAN LOPEZ, Leticia de la Caridad; SANTAMARIA LAFARGUE, Maritza; REVILLA MACHADO, Félix  and  DIAZ FERNANDEZ, Lilian. Alteraciones Inmunológicas en Niños con Enfermedad Diarreica Prolongada Y Parasitismo. Rev Cubana Pediatr [online]. 1999, vol.71, n.3, pp. 140-145. ISSN 1561-3119.

325 children between 8 months and 6 years old that were attended at the Immunology Department were studied from January, 1993, to June, 1997, in order to evaluate the relationship existing between prolonged diarrheal disease, intestinal parasitism and the alterations of the immune system. Quantitation of serum immunoglobulins (IgG, IgA and IgM) (n:157) was conducted. The skin test of delayed hypersensititvity with tetanus toxoid (n:60) was also carried out. The thymic area was measured by ultrasonography (n:108). Of the patients with low levels of immunoglobulins, 77 % presented deficient IgA. The tetanus toxoid test showed that 85 % of the patients studied had a deficit of functional cellular immunity, whereas 75 % of the total of patients had a diminished thymic area and of them 42 (39 %) had severe atrophy of this orgam. This allows us to conclude that the deficit of cellular immunity predominates in these cases and that it is necessary to use an adequate immunotherapy.

Keywords : SERUM GLOBULINS [inmunol]; TETANUS TOXOID [uso terap]; INFANTILE [terap].

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