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Revista Cubana de Pediatría
On-line version ISSN 1561-3119
Abstract
ACOSTA DIAZ, Ramón; VALDES DIAZ, Marta and PORTAL MIRANDA, María Elena. Prematuridad extrema y uso materno de corticoides antenatal. Rev Cubana Pediatr [online]. 2000, vol.72, n.4, pp. 281-286. ISSN 1561-3119.
In order to evaluate the antenatal use of adrenal cortex hormones in mothers with preterm delivery threat and its effect on extreme premature infants, it was conducted a prospective, longitudinal and analytical study among the live births with gestational age under 31 weeks and a weight lower than 1 500 g registered at "Justo Legón Padilla" Provincial Gynecoobstetric Teaching Hospital, in Pinar del Río, from January, 1997, to July, 1998. 53 children with these characteristics were studied. The collected data were entered in databases. The chi square test with a level of significance of p<0.05 was used for the statistical processing. Steroids were administered to 32 mothers. A statistically significant reduction of the hyaline membrane disease, the use of ventilation, the complications and mortality was observed with the antenatal use of maternal adrenal cortex hormones. There were no statistically significant differences between the study and the control group as regards sex, mean gestational age (29.0/28.9 weeks) and weights (1207.9/1180.0 g).
Keywords : INFANT PREMATURE; ADRENAL CORTEX HORMONES [administration & dosage]; GESTATIONAL AGE; HYALINE MEMBRANE DISEASE; RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL RESPIRATION.