Abstract

DURAN CASAL, Diana P. et al. IgA nephropathy: clinical and histological aspects. Rev Cubana Pediatr [online]. 2004, vol.76, n.4, pp. 0-0. ISSN 1561-3119.

The purpose of this paper was to know the clinical and histological characteristics of IgA nephropathy at the Nephrology Services of “Centro Habana” Pediatric Teaching Hospital.To this end, a retrospective study was conducted among 56 patients with the diagnosis of IgA: 36 males and 20 females aged 3-15. IgA neprhopathy accounted for 11.8 % of the total of the primary glomerulopathies in our study. The most frequent age group at the beginning of the disease was between 11 and 15 years old, with a predominance of males (64.2%). Recurrent macroscopic hematuria was the most common clinical form of presentation preceded from one to threee days by or concomitant with infection of the upper respiratory tract in most of the patients (57.1 %). In 67.8 % of the cases, the histological pattern found was pure mesangial proliferation (type II) and it was correlated with recurrent hematuria as an initial form of clinical presentation of the disease (92 %).

Keywords : IgA neprhopathy; Berger's disease; recurrent hematuria; immunofluorescence.