Abstract

VILLEGAS CRUZ, Débora et al. Hemolytic disease of the newborn due to ABO incompatibility. Rev Cubana Pediatr [online]. 2007, vol.79, n.4, pp. 0-0. ISSN 1561-3119.

The hemolytic disease of the newborn  due to ABO  incompatibility is the most frequent of all the blood group incompatibilities between the mother and the infant. 46 infants at term, who were diagnosed this disease at Enrique CabreraNational Hospital from June 2004 to March 2006, were studied. The diagnosis was made by physical examination, lab tests and immunohematological tests: ABO phenotyping, direct Coombstest, and the maternal IgG anti-A/B titer. 60.8 % of the newborn infants affected were phenotype A and their mothers were phenotype O. the direct Coombstest yielded positive in 2 cases. The maternal IgG titer in these cases was higher than or equal to 1024. Phototherapy was the most used treatment modality. Although this entity is the least severe of all the blood grouping conflicts between the mother and the infant, one should be alert before an unusual course to apply the optimal treatment at the right time  to reduce morbidity.

Keywords : Newborn hemolytic disease; direct Coombstest; phenotype.

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