Abstract

MORALES LEIVA, Milagros; LUIS ALVAREZ, María del Carmen; SEIGLIE DIAZ, Frances  and  PANTOJA PEREDA, Odette. Clinical-epidemiological behavior of Kawasaky' disease. Rev Cubana Pediatr [online]. 2011, vol.83, n.2, pp.158-165. ISSN 0034-7531.

INTRODUCTION. The Kawasaki's disease is a systemic, acute, febrile of auto-course vasculitis with a high risk of sequelae in children under 5 years old if it is not diagnosed and treated in its early stage. The aim of present study was to describe the clinical-epidemiological behavior of the Kawasaki's disease in childhood. METHODS. A descriptive study was conducted of the clinical and epidemiological features of patients diagnosed with Kawasaki' disease seen in the "William Soler" Children Hospital between January, 2002 and December, 2009. The study variable were: age, sex, clinical manifestations, date of symptoms onset and of the diagnosis, complementary examinations and treatment and response to treatment. RESULTS. The 100% of patients were under 8 years old. The 57,1`% was of male sex. The disease was more frequent in drought season. Fever was documented n the 100% of patients during more than 5 days of course, conjunctival injection, oropharyngeal lesions and plantar and palmar erythema; in the 85,7% of patients there was a polymorphous exanthema and in the 57,1%, a cervical unique adenopathy. The erythrosedimentation was high in the 100% of cases and in the 85,7% anemia was diagnosed. Three patients (42,8%) has coronary irregularities. All patients were treated with intravenous immunoglobulin (Intacglobin) and aspirin; in three of cases it was necessary to administer a second dose of intravenous immunoglobulin.

Keywords : Kawasaki; lymphomucocutaneous syndrome; systemic vasculitis; intravenous immunoglobulin.

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