Abstract

CHANG GOMEZ, Adalfa; FIGUEROA GARCIA, Iglermis; LAHERA SANCHEZ, Tania  and  GONZALEZ HERNANDEZ, Obdulio. Sensitization to domestic mites identified in severe asthmatic patients. Rev Cubana Pediatr [online]. 2013, vol.85, n.3, pp.311-319. ISSN 0034-7531.

Introduction: the prevalence of allergic diseases and asthma grows in Cuba and worldwide. Dust mites are one of the most prevailing perennial allergens throughout the world. Objective: to determine the sensitization to 3 domestic mite species of severe asmathic children from "Celia Sanchez Manduley" special school located in Tarara, Havana province. Methods: a cross-sectional descriptive study was carried out in 91 students during the 2011-2012 academic year. The whole sample was performed prick tests using Vallergen-BT (Blomia tropicalis), Vallergen-DS (Dermatophagoides siboney) and Vallergen-DP (Dermatophagoides pteronyssinus) extracts prepared by the National Center of Biopreparations and their total serum IgE were additionally estimated. Results: allergic rhinitis proved to be the most frequent comorbidity. All the patients showed positive skin reactivity to mites as well as increased total serum IgE. Sensitization to D. pteronyssinus was reported in 93.4 % of patients. There was no statistically significant difference in the habon diameter, but total serum IgE positivity and skin sensitization to the three dust mites under study were correlated. Conclusions: there is close association between bronchial asthma and sensitization to mites, being D. Pteronyssinus predominant.

Keywords : severe bronchial asthma; mites; IgE; skin sensitization.

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