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Revista Cubana de Pediatría

Print version ISSN 0034-7531On-line version ISSN 1561-3119


HERNANDEZ VELASCO, Thays; SEOANE PIEDRA, Janet  and  PEREZ CHIO, Ileana María. Early intervention in a newborn with agenesis of the corpus callosum. Rev Cubana Pediatr [online]. 2020, vol.92, n.4, e1288.  Epub Dec 01, 2020. ISSN 0034-7531.


The program of early stimulation in the early childhood is designed to foster and improve neurodevelopment. The callused body is a curved mass of a white substance composed by a beam of transverse fibers located in the back of the longitudinal track that connects both brain hemispheres. It is associated to prematurity and advanced maternal age.


To prove the validity of an early intervention program in the evolution of a patient with agenesis of corpus callosum in the stages of neurodevelopment.

Case presentation:

Venezuelan newborn, 4 months old, masculine, white skin, product of a second pregnancy. Young parents, no blood relation. At 19 weeks of pregnancy, it is conducted a fetal echography: interhemispheric cystic image, suggestive to agenesis of the corpus callosum. Emergency cesarean section at 34 weeks of pregnancy due to: IUGR, severe oligoamnios; acute fetal distress and preeclampsia, with 7-9 Agar, weight: 1800 g. The newborn was admitted in ´´La Pradera´´ International Health Center with a diagnosis of agenesis of the corpus callosum, and delay in the psychomotor development. It was started a program of early intervention five times in the week with four-monthly assessments. Relatives were involved in the program. At 18 months old, the patient achieved the longitudinal milestones of that age.


Early interventions favour brain neuroplasticity mechanisms, and provide a satisfactorily evolution in the stages of neurodevelopment, obviating the agenesis of the corpus callosum. Intensive participation of the child’s mother is essential for the success of the intervention.

Keywords : agenesis of the corpus callosum; neurodevelopment; early intervention; neurorehabilitation.

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