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Revista Cubana de Pediatría

On-line version ISSN 1561-3119


ROJAS MARRERO, Alejandro; MORALES GONZALEZ, Alejandro; ACOSTA TORRES, José  and  CARRION MENDOSA, Reinaldo. Onset nephrotic syndrome associated with SARS-COV-2 infection in a child. Rev Cubana Pediatr [online]. 2022, vol.94, suppl.1  Epub May 20, 2022. ISSN 1561-3119.


SARS-COV-2 infection affects different organs in its evolution, including the kidney.


To examine the unusual case of a patient affected by COVID-19, who showed a clinical and humoral picture compatible with nephrotic syndrome.

Case presentation:

One-year-old patient with a history of good health, without previous kidney disease, referred to Cerro Pediatric Hospital due to respiratory manifestations, marked edema and positive to SARS-COV-S antigen test. On admission, a weight of 14 kg, anasarca, blood pressure of 100/60 mmHg were observed. In the complementary tests, positive PCR to SARS-COV-2, hypoproteinemia, proteinuria and hypercholesterolemia were verified. Abdominal and thoracic ultrasound showed ascites and pleural effusion.


Preschool patient, admitted due to respiratory and hydropygenic syndrome and positive PCR to SARS-COV-2. The patient showed the clinical and humoral indicators compatible with nephrotic syndrome, with optimal response to steroid treatment. This case could constitute a coincidence or an unusual form of presentation of COVID-19 and therefore help a better knowledge of the syndrome and the initial clinical picture that could cause this new morbidity.

Keywords : SARS-COV-2; nephrotic syndrome; albuminuria; cytokines; immunosuppressant.

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