Abstract

HERNANDEZ ALVAREZ, Dinorah; GONZALEZ LAVAUT, José Antonio; PRIETO GONZALEZ, Silvia  and  TORRES LLACSA, Mabel. Carboprost methyl. Part II. Obstetric clinical uses. Rev Cubana Obstet Ginecol [online]. 1996, vol.22, n.2, pp. 0-0. ISSN 1561-3062.

Carboprost has been clinically evaluated in the induction of abortion by intravaginal route during the first trimester and in the pretreatment of the induction of abortion on the second month of pregnancy. It is also efficient to terminate pregnancy when it is administered by intraamniotic route. Its administration by intramuscular route is unpracticable due to its gastrointestinal toxicity; however, many authors recommend this route in the cases of deferred abortion, in intrauterine fetal death, and in other types of abnormal pregnancies. It has been used intravenously to control postpartum hemorrhage. Its intravesical administration has been used to treat hemorrhagic cystitis induced by cyclophosphamide, where it appears to be an effective and safe therapy.

Keywords : CARBOPROST [therapeutic use]; ABORTION, INDUCED; CYSTITIS [drug therapy]; POSTPARTUM HEMORRHAGE [drug therapy].