Abstract

RODRIGUEZ CARDENAS, Antonio  and  VELASCO BOZA, Alejandro. Use of 600 mg of Misoprostol to induce early abortion. Rev Cubana Obstet Ginecol [online]. 2003, vol.29, n.1, pp. 0-0. ISSN 1561-3062.

The objective of this study was to evaluate the efficacy and safety of the self-administration of 600mg of Misoprostol by the vaginal route up to three doses every 8 hours in a period of 24 hours so as to induce abortion in up to 9-week pregnancy. A group of pregnant volunteers with gestation times ranging from 35 to 63 days participated in the study. All the patients who had abortion received an additional dose of 600mg of Misoprostol. A patient decided not to continue in the study after the first interview but her data were included in the general characteristics of the sample. The method was considered to be efficient when it caused complete abortion without requiring further surgical or causing secondary effects. Fifty seven patients (64%) had complete abortion. The time of expulsion was 7,4 ± 3,8 h (median 7,2h, range 3-20h) for all the patients who had abortion in the first 24 hours of Misoprostol administration. Thirsty two cases failed, 28 were due to problems with the method after administering the third doses and 4 cases were due to medical decision. The obtained results in this study allowed us to conclude that the dose of 600mg of Misoprostol is not the adequate dose to produce high or acceptable abortive efficacy

Keywords : MISOSPROSTOL [therapeutic use]; ABORTION; INDUCED [methods].