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Revista Cubana de Obstetricia y Ginecología

On-line version ISSN 1561-3062


SARDUY NAPOLES, Miguel et al. Low degree cervical intraepithelial lesions. Regression, persistence, and progression after two years of evolution. Rev Cubana Obstet Ginecol [online]. 2009, vol.35, n.3, pp. 0-0. ISSN 1561-3062.

Many researchers confirm that the cervical scamous cancers are caused by cervical intraepithelial neoplasms (CIN). A meta-analysis reported that CIN I have a global mean incidence of progression to in situ carcinoma of 11% and of 19% to invasive cancer. In past years, expected behavior has been adopted in concordance with publications signaling little progression or up a normalization of these lesions. AIMS: To assess the evolutionary behavior of the CINs I and also to know some clinical and sociodemographic factors of patients presenting these lesions. METHODS: An observational and prospective study was carried out in Genecology Service of Medical Surgical Research Center in 55 women diagnosed with CIN I from January,1994 to December, 1995. RESULTS: The 74,6% had between 25 and 39 years old. The 80% had its first sexual intercourse before 20 years old. Smoking was referred by the 12,7%. Use of hormonal contraceptives was of 14,5%. At two years of course: cytology tests were negative in 72,7%, CINs I persisted in 10,9%, and 9,1% had a disease progression at this stage. CONCLUSIONS: CIN I was the more frequent entity in women in reproductive age, and those having its sexual life before 20 years old. Lesions regression was present in more than 7 of each 10 women, persisting in almost 2 of each 10, and disease progression in 1 of each 10.

Keywords : Low grade-cervical intraepithelial lesions; CIN I; expected behavior; progression; regression.

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