Abstract

RIOS HERNANDEZ, María de los Ángeles et al. The more frequent types of human papillomavirus in Cuban samples of cervix cancer. Rev Cubana Obstet Ginecol [online]. 2010, vol.36, n.2, pp. 104-111. ISSN 0138-600X.

Cervix cancer (UCC) is considered a sexually transmitted disease due to factors involved in its appearance and development and this infection is recognized as the main etiological agent of this entity. In Cuba this type of tumor is placed in 2^nd category in incidence and in 4^th place in mortality among the malignant disease affecting the female sex. The objective of present study is to determine the types of human virus papiloma (HVP) present in samples of cervix tumors in Cuban women, as well as to describe the behavior of different risk factors associated with this disease. Forty five samples of cervix cancer were analyzed and the presence of 20 types of HVP was determined by polymerase chain reaction with specific primers founding in them a 91,1% of positivity. Genotype 16 was the more prevalent, followed by the 18, 45, 31, 39, 51, 56, 59, PAP23A. The low risk type 6 and 11 weren't founded in samples. Promiscuity was the more interesting risk factor in our study. Knowledge of the viral types present in cervix cancer in our patients is very important when we approach the development and the use of prophylactic and therapeutical vaccines.

Keywords : Cervix cancer; human papilomavirus; polymerase chain reaction.

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