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Revista Cubana de Obstetricia y Ginecología

On-line version ISSN 1561-3062


CANCIANO CHIRINO, Ernesto; LOPEZ SILVERIO SANCHEZ, Reina M.  and  ALVAREZ DELGADO, Yamilé. Euthyroid nodule associated with pregnancy, some interesting variables for a regional multidisciplinary team. Rev Cubana Obstet Ginecol [online]. 2010, vol.36, n.4, pp. 502-509. ISSN 1561-3062.

The 4.96 % of the population presenting with a thyroid nodule with a great prevalence in fertile women, recognizing the pregnancy as a malignancy accelerator factor. A prospective and longitudinal study was conducted to characterize diagnostic-epidemiological features related to final course of euthyroid nodule associated with pregnancy in patients seen in a regional clinical-obstetrical consultation of the Havana's west from January, 2004 to October, 2009, identifying age according to number of previous pregnancies, nodule size by US y pregnancy time, mother/fetal complications and ethnic group and more anatomical-pathological diagnoses. By convenience 90 pregnants were sampled using clinical and ulrasonography criteria of the thyroid normofunctional nodule. There were predominance of patients aged between 25-29 and the 72.5 % had two or more previous pregnancies with a few children and a significant correlation coefficient for age according to previous pregnants. At the second trimester they had nodular echography measures more than 2 cm (33 pregnants) increasing the size according to the gestational time y estimated intra-class correlation coefficient . Gestational high blood pressure was significant among the complications, with more black pregnants. The 27.5 % of fine needle aspiration biopsy (FNAB) was not conclusive with a diagnostic sensitivity of 72.5 %. Although at the end of pregnancy the nodular thyroid disease has not mother/fetal complications, these patients are young without a good control of fertility leading to an increase of thyroid malignancy risk, unlike the methods used for its diagnosis, the glandular functional status is a significant independent risk variable .

Keywords : Eurothyroid nodule; thyroid disease; pregnancy; anatomical-pathological.

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