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Revista Cubana de Obstetricia y Ginecología

Print version ISSN 0138-600X

Abstract

COTO RODEIRO, Remigio; VARONA SANCHEZ, Joel A; BORREGO LOPEZ, Julio A  and  FORMOSO MARTIN, Luis Ernesto. Results of screening on congenital adrenal hyperplasia in newborns. Rev Cubana Obstet Ginecol [online]. 2011, vol.37, n.2, pp.136-146. ISSN 0138-600X.

An evaluative, linear and retrospective study was conducted on the underway of the program from its implementation from November, 2005 to April, 2007 related to the following quality parameters: newborn's age at the sample take moment, time elapsed from its arrival to laboratory, samples quality, number of non-useful samples and number of high results, figure of municipalities receiving the SUMA laboratory services from the "Ramón González Coro" Gynecology and Obstetrics Teaching Hospital. A total of 7 780 newborns dry blood samples were analyzed using filter paper and the 62.2 % was carried out at fifth day over an average of 7 days between take and the reception in laboratory with a very good quality, there were 80 non-useful samples with a coverage of 99.98 % and a total of 43 high results and also we analyzed some factors influencing in levels of 17OH-Progesterone quantified in the UMELISA 17OH-progesterone Neonatal including: birth weight, gender, newborn age and date of take sample, gestational age (by menstrual cycle or date of last menstruation) at labor moment, quantity of fetus and the type of labor, noting an increase in levels of 17OH-progesterone in those with a low-birth weight, prematures and in cases of cesarean section and pregnancy of more than one fetus.

Keywords : Adrenal hyperplasia; genetic diseases; screening program.

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