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Revista Cubana de Medicina Militar

Print version ISSN 0138-6557On-line version ISSN 1561-3046


ALFONSO ALFONSO, Lázaro E.; NODA SARDINAS, Constantino L.; REYES MARTINEZ, Margarita L.  and  RODRIGUEZ ACOSTA, Mireida. Metabolism and immunology in traumatisms. Rev Cub Med Mil [online]. 1999, vol.28, n.1, pp.55-66. ISSN 0138-6557.

Traumatisms are a severe and disabling affection that caused 5 450 deaths in Cuba, in 1997. Most of them resulted from generalized sepsis and multiple systems organ failure, the commonest cause of death in these patients, despite the progress attained in antibiotic therapy and in the anesthetic and reanimation techniques. A review of the physiological alterations they produce was made, making emphasis on their inmunodepressive effect and differentiating the inflamatory response to trauma known among the most severe patients as incontrolled and hypertensive immunohumoral response or malignant inflamatory response. The role played by the mediators of inflamation in itself, as well as the ways to fight immunodepression are approached. It was concluded tha the decrease of the post traumatic immune response may be measured, prevented and corrected, or at least modified with drugs and supplementary nutritional support.

Keywords : WOUNDS AND INJURIES [immunology]; WOUNDS AND INJURIES [metabolism].

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