Abstract

PADRON SANCHEZ, Armando; BRAVO PEREZ, Rigoberto; PUGA TORRES, Mario Santiago  and  JOANES FIOL, Javier. Door-drug interval. Rev Cub Med Mil [online]. 2001, vol.30, suppl.5, pp.41-46. ISSN 0138-6557.

Sixty-seven patients with acute myocardial infarction were studied, who had been applied a streptokinase-based thrombolytic treatment in the Emergency service of “Dr Luis Díaz Soto” Higher Institute of Military Medicine. The sample was divided into 2 groups: those who receive thrombolytics within 6 hours of the onset of symptoms (group A) and those who received them after 6 hours (group B). This variable was called door-drug interval. The objective was to define how the door-drug interval influences on the course and complication of the acute myocardial infarction. The group A patients had less mechanical complications and heart failure, more supraventricular arrhythmias and the difference of ST segment regression was higher, but their progression was more favorable than that of the group B patients. It is concluded that the use of thrombolytic therapy in the acute myocardial infarction should begin as soon as possible to reduce risks of future complications.

Keywords : MYOCARDIAL INFARCTION [drug therapy]; FIBRINOLYTIC AGENTS [therapeutic use]; INTENSIVE CARE UNITS.

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