Abstract

GARCIA MOREIRA, Tania et al. Topographic and anatomopathological correlation in the sellar region tumors. Rev Cub Med Mil [online]. 2008, vol.37, n.3. ISSN 0138-6557.

The high prevalence of hypophyseal macroadenomas worlwide motivated us to carry out this research, whose fundamental aim was to demonstrate the value of CT in the presumptive diagnosis of the histological variety of hypophyseal macroadenomas, as well as of other less frequent tumours of the sellar region, considering the clinical picture. To this end, 124 patients operated on with a clinical and tomographic diagnosis of hypophyseal macroadenomas and other tumours were studied. Age, sex, hospital stay, tomographic signs, and postsurgical anatomopathological results were registered. The highest incidence was found in the hypophyseal adenomas (110), with predominance of the non-secreting adenomas (41.1 %). Most of the patients were 30-50. The female sex prevailed in the adrenocorticotropic adenomas and meningiomas, and the male sex in gonadotropin and prolactin-producing adenomas. Within the tomographic signs the erosion of the clinoid and sellar dorsum, and hydrocephalus, predominated in the non-secreting adenomas and in the non-adenohypohyseal tumours. The gonadotropin-producing adenomas stood out in the erosion of the floor and in sellar ballooning as well as the adrenocorticotropic adenomas. The calcifications were more common in teratomas and craniopharyngiomas, as well as and the non-homogenous capture of the contrast agent, which was characteristic in these cases, as in Rathke's pouch cysts. CT showed its great diagnostic value in hypophyseal macroadenomas, and other tumours of the sellar region, taking into account the patient's clinical picture.

Keywords : Tumour; sellar region; CT; adenoma; hypophysis.

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