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Revista Cubana de Medicina Militar

Print version ISSN 0138-6557On-line version ISSN 1561-3046


NODARSE HERNANDEZ, Rafael. Detection of methicillin-resistant Staphylococcus aureus by cefoxitin sodium disc. Rev Cub Med Mil [online]. 2009, vol.38, n.3-4. ISSN 0138-6557.

OBJECTIVE. To detect the presence of Methicillin-resistant Staphylococcus aureus in patients from the «Dr. Luís Díaz Soto» Central Military Hospital. METHODS. The 30 µg-cefoxitin diffusion disk method was used. Analysis period was between July, 2006 to February, 2007 and 125 Staphylococcus aureus strains were studied. RESULTS. There was a 73.6 % of methicillin-sensitive of strains and to most of beta-lactamase antibiotics; the 26.4 % were methicillin-resistant Staphylococcus aureus strains. In hospital associated staphylococcus, percentage of above mentioned staphylococcus increased to almost the 45 %. Most of isolations were in Burn Ward and in Adult Intensive Care Unit (68 % for both). From the samples took in hospital environment (25) there was predominance of burns, bronchial secretion and the skin lesions (17); in ambulatory patients (8) samples took were from the skin lesions and soft tissues (8). Most of the Methicillin-resistant S. aureus strains (66.6 %) were Cefoxitin- resistant. No study staphylococcus was Vancomycin-resistant. There were not differences among the hospital Methicillin-resistant S. aureus and the community ones as regards its resistance patterns; we demonstrated high resistance values for almost all the study antibiotics, except the Vancomycin. CONCLUSIONS. Cefoxitin disk was useful to detect the Methicillin-resistant S. aureus and to predict its behavior versus other antibiotics. We verify that above mentioned Staphylococcus were very resistant.

Keywords : Methicillin-resistant Staphylococcus aureus; Cefoxitin; sensitivity to antibiotics.

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