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Revista Cubana de Medicina Militar

Print version ISSN 0138-6557


MOREJON PALACIOS, Edgar Luís et al. Primary retroperitoneal fibrosis. Rev Cub Med Mil [online]. 2012, vol.41, n.4, pp.407-414. ISSN 0138-6557.

Retroperitoneal fibrosis is a rare disease. Its epidemiology is a 1/1 million persons/year, It is more common in men than in women, ocuring in midle age, and its cause is primary or unknown in 75 % of cases. A 43 year-old patient, who had previous health history, referred to his family doctor not to feel well and with back pain associated with abnormalities of the urinary sediment, which was interpreted as urinary tract infection. Treatment started with ciprofloxacin antibiotic with no improvement. This patient was attended at nefrology guard, where emergency supplemental analysis were indicated. Results showed: creatinine values of 1024 micromol/L, high anion gap metabolic acidosis, and hydronephrotic kidney ultrasound. three hemodialysis sessions were indicated. At discussion of complex cases, a retroperitoneal fibrosis diagnosis was assessed, which was confirmed by CT scan at 72 hours of hospital arrival. Methylprednisolone therapy during three days was iniciated, followed by prednisone and cyclophosphamide for two years, with blood chemistry studies, complete blood count, and urine studies in correspondence with treatment response. complete remission of the disease without relapse was achieved.

Keywords : retroperitoneal fibrosis; hemodialysis; hydronephrosis; cyclophosphamide; methylprednisolone; prednisone.

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