Abstract

PEDRO, Más Lago et al. Nuevas evidencias de la relación antigénica entre los virus de la neuropatía epidémica y el sistema nervioso humano: Estudio de la respuesta inmune celular en pacientes con neuropatía epidémica y controles. Revisión del tema. Rev Cubana Med Trop [online]. 1998, vol.50, suppl.1, pp.249-353. ISSN 0375-0760.

A series of experiments was made at the Virology Department of the "Pedro Kourí" Institute of Tropical Medicine aimed at obtaining new evidences on the possible antigenic relations existing between the viruses isolated from patients with epidemic neuropathy and the structures of the human nervous system. According to the results it may be finally inferred that the persistance and/or autoimmunity may be considered as mechanisms through which the studied viruses participate in the etiopathogeny of the epidemic neuropathy in Cuba. For future experiments it is very important to identify the possible viral epitopes involved in the mollecular mimicry that are responsible for the probable autoimmune mechanisms or for the viral persistance.

Keywords : NEURITIS [etiology]; NEURITIS [cerebrospinal fluid]; NERVOUS SYSTEM [immunology]; CUBA.

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