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Revista Cubana de Medicina Tropical
On-line version ISSN 1561-3054
Abstract
PEREZ BASTAN, Jesús Enrique and VIANA CASTANO, Luisa Fernanda. Factors associated with non-adherence to antiretroviral therapy among people with HIV / AIDS. Rev Cubana Med Trop [online]. 2020, vol.72, n.2 Epub Oct 20, 2020. ISSN 1561-3054.
Introduction:
Non-adherence to antiretroviral therapy is one of the causes of the fast progression to AIDS among seropositive individuals.
Objective:
Identify the factors associated with non-adherence to antiretroviral therapy among people living with HIV / AIDS.
Methods:
An analytical cross-sectional study was conducted of 153 HIV / AIDS patients aged 18 years and over from Marcios Manduley polyclinic, municipality of Centro Habana, in the year 2018. Data were obtained from individual and family medical records, and a structured questionnaire was applied to complement the information required. The relationship between the variables was determined with the chi-square test ((2) with a statistical significance of p= 0.05, and variables were identified whose coefficients were significantly different from 0 (p< 0.05). Causality was determined by odds ratio (OR) estimation.
Results:
A statistical association was found, as well as the following risk factors for poor adherence to therapy: low educational level, frequent change of sexual partner, dysfunctional family, therapy duration longer than 5 years and adverse reactions.
Conclusions:
The study made it possible to identify the main variables associated to poor adherence to therapy among these patients, contributing scientific evidence for an appropriate control of the disease.
Keywords : human immunodeficiency virus; acquired immunodeficiency syndrome; adherence to therapy; risk factors.