Abstract

ALFONSO VALDES, María E et al. Hemotherapy in bone marrow transplantation: Experience at the Institute of Hematology and Immunology. Rev Cubana Hematol Inmunol Hemoter [online]. 1999, vol.15, n.2, pp. 121-126. ISSN 1561-2996.

The hemotherapy applied to 19 patients with malignant hematological diseases that underwent autologous bone marrow transplantation (n=10) and allogeneic bone marrow transplantation (n=9) is described. The average consumption of erythrocytes concentrates and of platelets concentrates was 6.1 and 57.3 respectively. The use of both component was higher among those patients that received an allogeneic bone marrow. The patients who were treated with cyclosporine required a higher number of erythrocyte and platelet concentrates than those who did not receive this immunosupressor. As ABO donor-recepient incompatibility was observed in 3 cases, some measures were taken to prevent posttransplantation hemolysis. In the case with mejor incompatibility erythrocytes were eliminated from the bone marrow, the recipient underwent plasmaphaeresises and received a transfusion of incompatible ABO erythrocytes. In the case with minor incompatibility, plasma was removed from the bone marrow. In 1 case with mixed incompatibility the measures taken in the previous cases were combined. There was no posttransplantation hemolysis in any of the cases

Keywords : LEUKEMIA [therapy]; LYMPHOMA, LYMPHOBLASTIC [therapy]; BLOOD; BONE MARROW, TRANSPLANTATION; TRANSPLANTATION HOMOLOGOUS; TRANSPLANTATION, AUTOLOGOUS.

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