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Revista Cubana de Hematología, Inmunología y Hemoterapia

On-line version ISSN 1561-2996

Abstract

RIVERO, Ananidia et al. Evaluation of the Cuban anti-A Hemo CIM and anti-B Hemo CIM monoclonal hemoclassifiers in HIV/AIDS patients. Rev Cubana Hematol Inmunol Hemoter [online]. 2000, vol.16, n.3, pp. 211-215. ISSN 1561-2996.

A study conducted with the Cuban anti-A and anti-B Hemo CIM monoclonal hemoclassifiers produced by the Center of Molecular Immunology (CMI) and commercialized by CIMAB S.A. to be evaluated in HIV/AIDS patients is described. 130 patients were analyzed at the Service of Transfusions of "Pedro Kouri" Institute. The polyclonal antisera of national production (Betera Laboratories) and the commercial monoclonal reagents produced and donated by the International Blood Group Reference Laboratory; Bristol, UK, were used at the same time. It was proved that the anti-A Hemo CIM and anti-B Hemo CIM reagents behaved similarly to their commercial and polyclonal homologues. On comparing the effectiveness of the agglutination for the 3 reagents, we were able to verify that the best results expressed in crosses were obtained with the anti-A and anti-B Hemo CIM monoclonal reagents

Keywords : ANTIBODIES, MONOCLONAL; HEMAGGLUTINATION TESTS; HIV.

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