Abstract

FUNDORA SARRAFF, Teresa A et al. The calculation of plasma volume by the clearance curves of the trasnferrin marked with Fe. Rev Cubana Hematol Inmunol Hemoter [online]. 2001, vol.17, n.1, pp.35-40. ISSN 0864-0289.

The plasma volume was calculated with transferrin marked with 59Fe (Tf-59FE) in 2 groups of patients, one with polycythemia vera and the other with relative polycythemia (RP), by using 2 methods: with the value of the activity at zero time obtained by regresssion and with the recounts per minute of a sample taken 3 minutes after the injection of Tf-59Fe. In all the cases, the activity at zero time was higher than the activity of the sample 3 minutes later. The values of plasma volume calculated by the first method were lower. The differences in the group with PV were significantly higher than the ones found in the group with RP. This study confirms the usefulness of calculating the distribution of Tf-59Fe at zero time when this has been homogeneously mixed in the circulation and the changes in the clearance curve are less critical

Keywords : RECEPTORS, TRANSFERRIN; PLASMA VOLUME; POLYCYTHEMIA VERA.

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