Abstract

CASTILLO GONZALEZ, Dunia de la C; ALMAGRO VAZQUEZ, Delfina  and  DIAZ CONCEPCION, Alina. Lupus anticoagulant in autoimmune diseases. Rev Cubana Hematol Inmunol Hemoter [online]. 2004, vol.20, n.2, pp. 0-0. ISSN 1561-2996.

Venous thromboembolism is a well-known complication in different autoimmune diseases. It has been established that detection of lupus anticoagulant (LA) and possibly IgG type anticardiolipin antibodies (AAC) in high and medium titers help to identify patients with thrombosis risk. We studied LA in 81 patients with autoimmune erythomatous lupus, 28 patients with idiopathic thrombocytopenic purpura, 15 with autoimmune hemolytic anemia and 13 patients who were included in the group covering other diseases such as small vessel skin vasculitis, combined disease of the connective tissue, rheumatoid arthritis and sclerodermia. LA was found in 19,7 % of the total number of cases, in 16% of patients with LES, 21,4 % of those with ITP and 40 % of cases with AIHA. In the group of other diseases, there was no patient with positive LA. 56,3 % of patients with positive AL showed some manifestations related to antiphospholipid syndrome

Keywords : Lupus anticoagulant; antiphospholipid syndrome; autoimmune diseases; thrombosis.