Abstract

VILLARES ALVAREZ, Icilany et al. Ocular manifestations of drepanocytemia in adult patients resident in Cienfuegos province. Rev Cubana Hematol Inmunol Hemoter [online]. 2009, vol.25, n.2, pp.75-85. ISSN 0864-0289.

A cross-sectional and descriptive study was carried out to assess the ocular manifestations of drepanocytemia in 64 adult patients seen in Hemoglobinopathy of "Dr. Gustavo Aldereguía Lima" University Hospital. The aims of present paper were: to assess the ophthalmologic alterations frequency related to clinical-hematological parameters and to estimate its functional consequences. A basal total ophthalmologic examination was performed. For data analysis descriptive statistical models, mean comparisons and the Chi² test. The decimal point sign was the more frequent alteration associated with SS genotype and with lower hemoglobin levels. Vessel tortuous was the commonest finding in retina in all genotypes, whereas the vitreous body opacities and the black cupping in sun shape showed a statistically significant association in some cases. A non-proliferative retinopathy was diagnosed in most of study patients and in some of them the findings of both types of retinopathy were showed. Despite the numerous lesions showed, visual acuity was qualified as good in the 94,6% of study eyes.

Keywords : Sickle cell anemia; drepanocytemia; ocular manifestations; retinopathy.

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