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Revista Cubana de Hematología, Inmunología y Hemoterapia
Print version ISSN 0864-0289
Abstract
EXPOSITO DELGADO, Yesy Caterine; AGRAMONTE LLANES, Olga M. and MIGUEL MORALES, Maydelín. Sickle cell and cancer: a path to new research. Rev Cubana Hematol Inmunol Hemoter [online]. 2014, vol.30, n.3, pp. 202-213. ISSN 0864-0289.
Association between sickle cell disease and cancer has been reported for a long time. Among them, solid tumors in different locations of the body and hematological malignances have been diagnosed. Not only the severity of the neoplastic disease but also chronic organ involvement have influenced in patients´survival where the physiopathogenesis of the hereditary disease with high frequency determines a fatal outcome. Our goal is to make an updated review on such association as a warning, considering that the almost exclusive relationship of some cancers and hemoglobinopathy S is already known.
Keywords : sickle cell disease; neoplasias; hematologic malignancies.