Abstract

FERNANDEZ, Yusleidy Concepción et al. Autoimmune hemolytic anemia with cryoagglutinins and aplastic crisis in a patient with SC hemoglobinopathy. Rev Cubana Hematol Inmunol Hemoter [online]. 2019, vol.35, n.1 ISSN 1561-2996.

Infection with human B19 parvovirus is the cause of most cases of transient aplastic crisis that appear in patients with chronic hemolytic diseases, as in the case of sickle cell disease. On the other hand, a few cases of acute infection by human parvovirus B19 have been described as a cause of autoimmune hemolytic anemia, through the formation of antibodies directed against red blood cells. The association between sickle cell disease and autoimmune hemolytic anemia is rare. We report an unusual case of an adult patient, with a history of S C hemoglobinopathy who presented an aplastic crisis and subsequently an autoimmune hemolytic anemia diagnosed at the Institute of Hematology and Immunology, treated with high steroids doses, reaching the remission of autoimmune hemolytic anemia and constitutes the first report in Cuba.

Keywords : human B19 parvovirus; autoimmune; hemolytic anemia; aplastic crisis; SC hemoglobinopathy.

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