Introduction:

The search for treatment alternatives that allow reducing wound healing and hospitalization time are fundamental aspects in research nowadays. Platelet growth factors are capable of enhancing wound healing.

Objective:

Determine the benefits of applying homologous platelet lysate on the donor area of autologous skin graft.

Methods:

A prospective longitudinal-section study was conducted in 20 patients with bloody areas that required autologous skin graft at the “Hospital Hermanos Ameijeiras” between August 2016 and May 2019. Two graft intakes were made in the same patient and anatomical region, one of them treated with platelet lysate (intervention zone) and one with conventional treatment (control zone). Patients selection was intentional. Absolute numbers and proportions were used to study the qualitative variables, and measures of central tendency and dispersion were used in the quantitative variables. To compare de results, the Friedman test was applied, setting a level of significance p < 0,05.

Results:

The main cause of bloody area was burns (75 %), the most affected age group was those over 55 years, the healing percentage was greater in the intervention group with a statistically significant shorter epithelization time (p < 0,01) and there was less pain in the intervention zone. There were no complications.

Conclusions:

The benefits found in the intervened area with platelet lysate were significant with faster healing and less pain.

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