Abstract

FERNANDEZ-VALLIN CARDENAS, Eulalia; MONTANE JAIME, Karelia; MOLINA GARCIA, José Ramón  and  ALVAREZ CORREDERA, Mayra. Efectos de la teofilina sobre el tamaño celular y celularidad en ratones BALB/C durante la organogénesis. Rev Cubana Invest Bioméd [online]. 1996, vol.15, n.1. ISSN 0864-0300.

The effects of the administration of 7 mg/kg of body weight of daily intraperitoneal theophylline, is explored between days 8 and 14 of pregnancy in 28 BALB/C mice, on the DNA and protein contents of the fetuses at birth, and the estimators of size and cell amount. The results were compared with those from a 36 animals control group. Those results indicated that theophylline didn't significantly affect either the DNA and protein contents, or the size and cell amount of the fetuses.

Keywords : THEOPHYLLINE [pharmacokinetics]; DNA [drug effects]; PROTEINS [drug effects]; CELLS [drug effects]; FETAL DEVELOPMENT; MICE, INBRED BALB/C.